February 2022
- publication 268 selected as Top pick from the editor in chief of JACC
- interview ZonMW on GALANT https://publicaties.zonmw.nl/hartritmestoornissen-behandelen-door-cellen-te-verbeteren/
- Lisa Gottlieb graduated with her thesis: Atrial Fibrillation and the Pulmonary Veins.
January 2022
- Expert opinion JACC epicardial diseases: https://www.acc.org/Latest-in-Cardiology/Articles/2022/01/24/13/49/Modulation-of-Cardiac-Arrhythmogenesis-by-Epicardial-Adipose-Tissue
- JACC BTS 2021 Top reviewer recognition
July 2021
- 10 years of Frontiers: https://blog.frontiersin.org/2021/07/06/celebrating-a-decade-of-frontiers-in-physiology/
March 2021
- Chapter in the ESC textbook of Cardiology accepted
- Farewell Charly
- podcast on JACC website related to publication 253
- Burdon Sanderson revisited in publication 259
September 2020
- interview about the Galant project (Link)
- publication nr 250
August 2020
- 249: Collaboration with prof. Shivkumar's group.
July 2020
- DCVA IMPRESS granted!
- virtual summer school at LIRYC
- virtual Journal club meetings at LIRYC
June 2020
- Black swan published (publication 244)
April 2020
- Appointed Editorial Consultant JACC-CE
March 2020
- All experiments on hold. The group is working from home.
February 2020
- Visit to UCLA: a week of experiments
July 2019
- Summer School teaching at Liryc
May 2019
- Leducq midterm review in San Francisco: green light for continuation.
- TKI-grant about neurokinine agonists landed by Marieke Veldkamp.
December 2018
- Publication 223 in the top 1% of all papers published within the field of clinical medicine based on Web of Science’s highly cited threshold for the field and publication year.
November 2018
- Another week of successful experiments in Los Angeles at Shivkumar's lab.
September 2018
- Senktide paper accepted in Nature Communications (see publication nr 228)
July 2018:
- Visit to Bangkok (Nademanee's lab) for mapping of a patient with ERS.
June 2018:
- Coert Zuurbier landed a grant from the EFSD/Novo Nordisk Programme 2018 to study EMPAgliflozin.
February 2018:
- Laura Bear published a paper on LBBB in Heart Rhythm (publication 224)
- Abstracts accepted for the Heart Rhythm society meeting.
- Out of the Box-grant landed by Coert Zuurbier, Jolanda van der Velden, Antonius Baartscheer and Ruben Coronel.
November 2017:
- A week at UCLA doing experiments in the Shivkumar and Ardell labs, together with Veronique Meijborg, Bas Boukens, Giel Janse and Tobias Op 't Hof.
September 2017:
- hCPC paper accepted: a tribute to Janse et al 1980. Read the title!
August 2017:
- Paper on the role of biomaterials accepted in PLOS-ONE. It is the result of a collaboration between The AMC, Fuji-film and the University of Groningen.
July 2017:
- Game changer proposal ' GALANT' was granted.
This is the workplan:We will develop and apply breakthrough technologies: virally-delivered gene therapy targeted precisely, and minimally invasively, to the region of the heart where it is needed. First, we will optimize a loss of function mutation (G628S) in the KCNH2, the gene that encodes the IKr channel, and therefore can be used to prolong APD and prevent VT/VF. The construct must be targeted to the exit points of the VT/ VF reentrant circuit in the infarct region by using a noninvasive endo- and epicardial activation imaging system that we recently developed and validated. The system is based on body surface electrocardiographic mapping (BSM; 64 electrodes) in combination with thoracic CT or MRI-imaging. Third, we will target the G628S-KCNH2 construct precisely to the identified exit sites in pigs with myocardial infarction, using high precision catheter injection techniques, and will monitor the effect of the KCNH2-G628S construct (i.e. APD prolongation) at the injection site by combined non-invasive activation and repolarization time mapping.
April 2017:
- coverage in AMC Magazine. The RHYTHM-project.
January 2017:
- Last SHAPEHEART meeting in Amsterdam, preceded by a symposium with Sian Harding, Andre Terzic, Michel Puceat, Mark Mercola. Jolanda van der Velden.
December 2016:
- Review on fatty diets accepted by Pharmacology and Therapeutics.
- coverage in AMC magazine (see there)
November 2016:
- Bayer grant landed by Marieke Veldkamp
- publication 268 selected as Top pick from the editor in chief of JACC
- interview ZonMW on GALANT https://publicaties.zonmw.nl/hartritmestoornissen-behandelen-door-cellen-te-verbeteren/
- Lisa Gottlieb graduated with her thesis: Atrial Fibrillation and the Pulmonary Veins.
January 2022
- Expert opinion JACC epicardial diseases: https://www.acc.org/Latest-in-Cardiology/Articles/2022/01/24/13/49/Modulation-of-Cardiac-Arrhythmogenesis-by-Epicardial-Adipose-Tissue
- JACC BTS 2021 Top reviewer recognition
July 2021
- 10 years of Frontiers: https://blog.frontiersin.org/2021/07/06/celebrating-a-decade-of-frontiers-in-physiology/
March 2021
- Chapter in the ESC textbook of Cardiology accepted
- Farewell Charly
- podcast on JACC website related to publication 253
- Burdon Sanderson revisited in publication 259
September 2020
- interview about the Galant project (Link)
- publication nr 250
August 2020
- 249: Collaboration with prof. Shivkumar's group.
July 2020
- DCVA IMPRESS granted!
- virtual summer school at LIRYC
- virtual Journal club meetings at LIRYC
June 2020
- Black swan published (publication 244)
April 2020
- Appointed Editorial Consultant JACC-CE
March 2020
- All experiments on hold. The group is working from home.
February 2020
- Visit to UCLA: a week of experiments
July 2019
- Summer School teaching at Liryc
May 2019
- Leducq midterm review in San Francisco: green light for continuation.
- TKI-grant about neurokinine agonists landed by Marieke Veldkamp.
December 2018
- Publication 223 in the top 1% of all papers published within the field of clinical medicine based on Web of Science’s highly cited threshold for the field and publication year.
November 2018
- Another week of successful experiments in Los Angeles at Shivkumar's lab.
September 2018
- Senktide paper accepted in Nature Communications (see publication nr 228)
July 2018:
- Visit to Bangkok (Nademanee's lab) for mapping of a patient with ERS.
June 2018:
- Coert Zuurbier landed a grant from the EFSD/Novo Nordisk Programme 2018 to study EMPAgliflozin.
February 2018:
- Laura Bear published a paper on LBBB in Heart Rhythm (publication 224)
- Abstracts accepted for the Heart Rhythm society meeting.
- Out of the Box-grant landed by Coert Zuurbier, Jolanda van der Velden, Antonius Baartscheer and Ruben Coronel.
November 2017:
- A week at UCLA doing experiments in the Shivkumar and Ardell labs, together with Veronique Meijborg, Bas Boukens, Giel Janse and Tobias Op 't Hof.
September 2017:
- hCPC paper accepted: a tribute to Janse et al 1980. Read the title!
August 2017:
- Paper on the role of biomaterials accepted in PLOS-ONE. It is the result of a collaboration between The AMC, Fuji-film and the University of Groningen.
July 2017:
- Game changer proposal ' GALANT' was granted.
This is the workplan:We will develop and apply breakthrough technologies: virally-delivered gene therapy targeted precisely, and minimally invasively, to the region of the heart where it is needed. First, we will optimize a loss of function mutation (G628S) in the KCNH2, the gene that encodes the IKr channel, and therefore can be used to prolong APD and prevent VT/VF. The construct must be targeted to the exit points of the VT/ VF reentrant circuit in the infarct region by using a noninvasive endo- and epicardial activation imaging system that we recently developed and validated. The system is based on body surface electrocardiographic mapping (BSM; 64 electrodes) in combination with thoracic CT or MRI-imaging. Third, we will target the G628S-KCNH2 construct precisely to the identified exit sites in pigs with myocardial infarction, using high precision catheter injection techniques, and will monitor the effect of the KCNH2-G628S construct (i.e. APD prolongation) at the injection site by combined non-invasive activation and repolarization time mapping.
April 2017:
- coverage in AMC Magazine. The RHYTHM-project.
January 2017:
- Last SHAPEHEART meeting in Amsterdam, preceded by a symposium with Sian Harding, Andre Terzic, Michel Puceat, Mark Mercola. Jolanda van der Velden.
December 2016:
- Review on fatty diets accepted by Pharmacology and Therapeutics.
- coverage in AMC magazine (see there)
November 2016:
- Bayer grant landed by Marieke Veldkamp
